MedGames
Glycolysis Matching Game (intermediates only)
Glycolysis Matching Game (intermediate products and enzymes)
Important Points About Glycolysis:
Trapping Glucose in the Cell: Hexokinase is responsible for trapping glucose inside the cell by sticking a phosphate on it so it's too bulky to get out . In the liver, glucokinase replaces hexokinase.
The act of sticking a phosphate on the end is called phosphorylation and is done by "kinase" enzymes. Energy is used in this process.
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Energy using steps (2 ATP used):
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Glucose --> Glucose-6-Phosphate
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Fructose-6-Phosphate --> Fructose-1,6-bisphosphate
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Energy producing steps (4 ATP produced, 2 ATP net gain after replacing the initial 2 ATP used):
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1,3-bisphosphoglycerate --> 3-phosphoglycerate
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Phosphoenolpyruvate (PEP) --> Pyruvate
Review Videos:
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NinjaNerd Glycolysis and NinjaNerd Glycolysis Regulation- NinjaNerd videos are the best way to really understand a concept rather than just memorize it. These videos word from a pre-med, to RN, to med school level.
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Glycolysis Made Easy - Dr. Matt & Dr. Mike includes a little bit of everything. Mnemonics. Overview. Explanation.
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Muscle Metabolism Creatine Phosphokinase (CPK), Glycolysis, TCA cycle, ETC | Physiology - Medicosis Perfectionalis is more about the biochemical pathways and how they connect. This is good for biochemistry classes, physician's assistants, and medical school
Other Resources:
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Glycolysis in 10 Steps - MicrobiologyInfo.com shows the chemical structure of each intermediate so it's easier to visually follow what's happening with text and images
Mnemonics:
Intermediate Mnemonic (mildly inappropriate for those under 18)
Gross guys favor fat butts, good boys prefer pretty pink pajamas
Gross - glucose
Guys - glucose-6-phosphate
Favor - fructose-6-phosphate
Fat Butts - fructose-1,6-bisphosphate
Good - glyceraldehyde-3-phosphate
Boys - 1,3-bisphosphoglycerate
Prefer - 3-phosphoglycerate
Pretty - 2-phosphoglycerate
Pink - phosphoenol pyruvate
Pajamas - pyruvate
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Enzyme Mnemonic (crass, but effective. Please look elsewhere if you prefer to avoid inappropriate memory tools. Adjust wording to your personal preference).
Honestly - Hexokinase
Ignoring - Isomerase
Pen*s - PFK-1 *rate limiting step*
And - Aldolase
Getting - G3P dehydrogenase
P*s*y - Phosphoglycerate kinase
Made - Mutase
Everything - Enolase
Perfect - Pyruvate kinase
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